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 About 4 results found for searched term "Combretastatin A4" (0.127 seconds)

Cat.No.  Name Target
M2274 Fosbretabulin disodium Microtubule
Combretastatin A-4 phosphate, CA4P
Fosbretabulin disodium (Combretastatin A-4 phosphate) is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
M3901 Combretastatin A4 Microtubule
CRC 87-09, NSC 817373, CA-4
Combretastatin A4 (CA-4), which is a natural stilbene isolated from Combretum caffrum, is a microtubule-destabilizing agent that binds to the colchicine domain on β-tubulin and exhibits a lower toxicity profile than paclitaxel or the Vinca alkaloids.
M7500 YK 3-237 Sirtuin
YK 3-237 is a boronic acid chalcone analog of combretastatin a4 (CA-4) and a SIRT1 activator that targets mutant p53. YK 3-237 can reduce the acetylation of mutant p53 protein by activating the SIRT1 enzyme, resulting in a significant decrease in the level of mutant p53 protein. YK-3-237 showed antiproliferative activity against tumor cells containing mutant p53 protein.
M27742 isoCA-4  Microtubule
isoCA-4, a Combretastatin A4 derivative, is a tubulin polymerization inhibitor. isoCA-4 has anti-proliferative activities.



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